esm2_t33_650M_UR50D

esm2_t33_650M_UR50D

facebook

ESM-2 protein language model with 650M parameters. Trained on masked language modeling for protein sequences. Mid-tier model balancing performance and efficiency.

PropertyValue
Parameter Count650M parameters
LicenseMIT
AuthorFacebook
Model TypeProtein Language Model
Framework SupportPyTorch, TensorFlow

What is esm2_t33_650M_UR50D?

ESM2_t33_650M_UR50D is a medium-sized protein language model featuring 33 layers and 650 million parameters. It's part of Facebook's ESM-2 family of models, designed for protein sequence analysis through masked language modeling. This particular variant offers a balanced compromise between computational efficiency and performance.

Implementation Details

The model is implemented using both PyTorch and TensorFlow frameworks, supporting Fill-Mask operations and utilizing Safetensors for efficient tensor storage. It's trained on a masked language modeling objective, specifically designed for protein sequence analysis.

  • 33-layer transformer architecture
  • 650M parameter size - middle ground in the ESM-2 family
  • Supports both F32 and I64 tensor types
  • Trained on the UR50D dataset

Core Capabilities

  • Protein sequence analysis and prediction
  • Masked language modeling for protein sequences
  • Fine-tunable for various protein-related tasks
  • Sequence-to-sequence protein modeling

Frequently Asked Questions

Q: What makes this model unique?

This model represents a sweet spot in the ESM-2 family, offering good performance while being more manageable than larger variants like the 15B parameter model. It's particularly suitable for research and production environments where computational resources are limited but high-quality protein analysis is required.

Q: What are the recommended use cases?

The model is ideal for protein sequence analysis, structure prediction, and protein engineering applications. It can be fine-tuned for specific tasks like protein function prediction, stability assessment, and sequence generation.

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