prot_t5_xl_half_uniref50-enc

prot_t5_xl_half_uniref50-enc

Rostlab

Encoder-only half-precision protein language model based on T5 architecture, trained on UniRef50 dataset for efficient protein embedding generation with reduced GPU memory requirements.

PropertyValue
AuthorRostlab
ArchitectureT5-based Encoder-only
Training DataUniRef50
PrecisionFloat16 (Half-precision)
PaperProtTrans Paper

What is prot_t5_xl_half_uniref50-enc?

This model is a specialized half-precision version of the ProtT5-XL-UniRef50, designed specifically for efficient protein sequence embedding generation. Based on the t5-3b architecture, it's been optimized to work with minimal GPU memory requirements while maintaining performance quality. The model processes uppercase amino acid sequences to create meaningful protein representations.

Implementation Details

The model implements a modified T5 architecture, trained using a Bart-like MLM denoising objective with a 15% amino acid masking probability. It's particularly notable for its efficient memory usage, requiring only 8GB of video RAM.

  • Encoder-only architecture for efficient embedding generation
  • Half-precision (float16) parameters for reduced memory footprint
  • Trained on extensive UniRef50 protein sequence database
  • Supports batch processing of protein sequences

Core Capabilities

  • Generation of per-residue protein embeddings (1024-dimensional)
  • Creation of whole-protein representations
  • Efficient processing of large protein sequences
  • Support for batch processing of multiple sequences

Frequently Asked Questions

Q: What makes this model unique?

This model's uniqueness lies in its optimized half-precision implementation while maintaining the full capabilities of the original ProtT5-XL-UniRef50 model. It provides the same quality of protein embeddings but with significantly reduced memory requirements.

Q: What are the recommended use cases?

The model is ideal for creating amino-acid or protein embeddings in memory-constrained environments. It's particularly useful for downstream tasks such as protein structure prediction, function annotation, and protein property prediction.

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